The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti–PD-1 antibody

Don M. Benson, Courtney E. Bakan, Anjali Mishra, +14

Blood

Phase I Safety and Pharmacokinetic Study of CT-011, a Humanized Antibody Interacting with PD-1, in Patients with Advanced Hematologic Malignancies

Raanan Berger, Rinat Rotem‐Yehudar, Gideon Slama, +6

Clinical Cancer Research

PD-1–Expressing Tumor-Infiltrating T Cells Are a Favorable Prognostic Biomarker in HPV-Associated Head and Neck Cancer

Cécile Badoual, Stéphane Hans, Nathalie Merillon, +27

Cancer Research

Neck CancerHpv-associated HeadT-regulatory CellImmunologyCell Death +19

Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: a single group, open-label, phase 2 trial

Jason R. Westin, Fuliang Chu, Min Zhang, +19

The Lancet Oncology

Lymphoid NeoplasiaMedicineImmunologyPathologyImmune Checkpoint Inhibitor +8

Disabling Immune Tolerance by Programmed Death-1 Blockade With Pidilizumab After Autologous Hematopoietic Stem-Cell Transplantation for Diffuse Large B-Cell Lymphoma: Results of an International Phase II Trial

Philippe Armand, Arnon Nagler, Edie Weller, +21

Journal of Clinical Oncology

PD-1 Blockade by CT-011, Anti-PD-1 Antibody, Enhances Ex Vivo T-cell Responses to Autologous Dendritic Cell/Myeloma Fusion Vaccine

Jacalyn Rosenblatt, Brett Glotzbecker, Heidi Mills, +10

Journal of Immunotherapy

Active MyelomaPd-1 BlockadeImmunologyImmune RegulationCd4 T Cell Responses +17

Anti‐PD‐1 synergizes with cyclophosphamide to induce potent anti‐tumor vaccine effects through novel mechanisms

Mikayel Mkrtichyan, Yana G. Najjar, Estella C. Raulfs, +5

European Journal of Immunology

T-regulatory CellImmunologyImmunologic MechanismT CellsTcr Activation +15

Association of Insulin-like Growth Factor 1 Receptor with EHD1 and SNAP29

Rinat Rotem‐Yehudar, Emilia Galperin, Mia Horowitz

Journal of Biological Chemistry

LMP-associated proteolytic activities and TAP-dependent peptide transport for class 1 MHC molecules are suppressed in cell lines transformed by the highly oncogenic adenovirus 12.

Rinat Rotem‐Yehudar, Marcus Groettrup, Andrea Soza, +2

The Journal of Experimental Medicine

Mouse Tap GenesImmunologyViral PathogenesisAntigen ProcessingTap-dependent Peptide Transport +17

EHD3: A Protein That Resides in Recycling Tubular and Vesicular Membrane Structures and Interacts with EHD1

Emilia Galperin, Sigi Benjamin, Debora Rapaport, +3

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