Rosa Marı́a Rodrı́guez Sarmiento

Diversity oriented biosynthesis via accelerated evolution of modular gene clusters

Aleksandra Wlodek, Steve Kendrew, Nigel J. Coates et al. · Nature Communications · 2017 · 91 citations · Full text

A new class of histamine H3 receptor antagonists derived from ligand based design

Olivier Roche, Rosa Marı́a Rodrı́guez Sarmiento · Bioorganic & Medicinal Chemistry Letters · 2007 · 36 citations · Full text

Allergy, Functional Selectivity, Medicine +8

5-Hydroxyindole-2-carboxylic Acid Amides: Novel Histamine-3 Receptor Inverse Agonists for the Treatment of Obesity

Pascale David Pierson, Alec Fettes, Christian Freichel et al. · Journal of Medicinal Chemistry · 2009 · 33 citations · Full text

Aβ43‐producing <scp>PS</scp> 1 <scp>FAD</scp> mutants cause altered substrate interactions and respond to γ‐secretase modulation

Johannes Trambauer, Rosa Marı́a Rodrı́guez Sarmiento, Akio Fukumori et al. · EMBO Reports · 2019 · 31 citations · Full text

Design of Potent and Druglike Nonphenolic Inhibitors for Catechol <i>O</i>-Methyltransferase Derived from a Fragment Screening Approach Targeting the <i>S</i>-Adenosyl-<scp>l</scp>-methionine Pocket

C. Lerner, Roland Jakob‐Roetne, Bernd Buettelmann et al. · Journal of Medicinal Chemistry · 2016 · 28 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +15