Jiaoxiang Chen

STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway

Qiang Guo, Ximiao Chen, Jiaoxiang Chen et al. · Cell Death and Disease · 2021 · 230 citations · Full text

Parkin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration

Zengjie Zhang, Tianzhen Xu, Jiaoxiang Chen et al. · Cell Death and Disease · 2018 · 100 citations · Full text

TFEB protects nucleus pulposus cells against apoptosis and senescence via restoring autophagic flux

Gang Zheng, Zongyou Pan, Yu Zhan et al. · Osteoarthritis and Cartilage · 2018 · 93 citations

Cell Autophagy, Mitophagy, Nucleus Pulposus Cells +11

Celastrol reduces IL-1β induced matrix catabolism, oxidative stress and inflammation in human nucleus pulposus cells and attenuates rat intervertebral disc degeneration in vivo

Jian Chen, Jun Xuan, Yuntao Gu et al. · Biomedicine & Pharmacotherapy · 2017 · 91 citations

Regenerative Medicine, Inflammation, Degenerative Spine +10

Ligustilide alleviated IL-1β induced apoptosis and extracellular matrix degradation of nucleus pulposus cells and attenuates intervertebral disc degeneration in vivo

Ke Wang, Tingting Chen, Xiaozhou Ying et al. · International Immunopharmacology · 2019 · 85 citations

Inflammation, Degenerative Spine, Intervertebral Disc +13