Federica Cossu

TREX1 C-terminal frameshift mutations in the systemic variant of retinal vasculopathy with cerebral leukodystrophy

Jacopo C. DiFrancesco, Francesca Novara, Orsetta Zuffardi et al. · Neurological Sciences · 2014 · 59 citations

Ocular Disease, Retina, Vasculitis +11

Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2

Federica Cossu, Eloise Mastrangelo, Mario Milani et al. · Biochemical and Biophysical Research Communications · 2008 · 57 citations

Medicine, Mechanism Of Action, Peptide Synthesis +2

Structural Basis for Bivalent Smac-Mimetics Recognition in the IAP Protein Family

Federica Cossu, Mario Milani, Eloise Mastrangelo et al. · Journal of Molecular Biology · 2009 · 43 citations

Protein Assembly, Biochemistry, Natural Sciences +9

Targeting the X-Linked Inhibitor of Apoptosis Protein through 4-Substituted Azabicyclo[5.3.0]alkane Smac Mimetics. Structure, Activity, and Recognition Principles

Eloise Mastrangelo, Federica Cossu, Mario Milani et al. · Journal of Molecular Biology · 2008 · 40 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Drug Targeting +12

Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy

Pierfausto Seneci, Aldo Bianchi, Cristina Battaglia et al. · Bioorganic & Medicinal Chemistry · 2009 · 39 citations · Full text

Cancer Therapy, Rational Design, Proapoptotic Agents +8