The composition of house dust mite is critical for mucosal barrier dysfunction and allergic sensitisation

S. Post, Martijn C. Nawijn, Tillie‐Louise Hackett, +4

Thorax

Cigarette smoke-induced necroptosis and DAMP release trigger neutrophilic airway inflammation in mice

Simon D. Pouwels, G. Jan Zijlstra, Marco van der Toorn, +9

American Journal of Physiology-Lung Cellular and Molecular Physiology

AsthmaInflammatory Lung DiseaseLung InflammationImmunologyImmune Regulation +18

Indoleamine 2,3-dioxygenase–dependent tryptophan metabolites contribute to tolerance induction during allergen immunotherapy in a mouse model

Yousef A. Taher, Benoit Jaak Alain Piavaux, Renée Gras, +5

Journal of Allergy and Clinical Immunology

InflammationAllergyMedicineImmune RegulationImmunology +9

Critical role of aldehydes in cigarette smoke-induced acute airway inflammation

Marco van der Toorn, Dirk‐Jan Slebos, Harold G. de Bruin, +5

Respiratory Research

TLR-2 Activation Induces Regulatory T Cells and Long-Term Suppression of Asthma Manifestations in Mice

Martijn C. Nawijn, Alexandre C. Motta, Renée Gras, +3

PLoS ONE

AsthmaInflammatory Lung DiseaseLung InflammationT-regulatory CellImmunology +15

GITR signaling potentiates airway hyperresponsiveness by enhancing Th2 cell activity in a mouse model of asthma

Alexandre C. Motta, Joost L. M. Vissers, Renée Gras, +3

Respiratory Research

Pim1 kinase protects airway epithelial cells from cigarette smoke-induced damage and airway inflammation

Maaike de Vries, Irene H. Heijink, Renée Gras, +8

American Journal of Physiology-Lung Cellular and Molecular Physiology

AsthmaPim KinasesInflammatory Lung DiseaseLung InflammationImmunology +20

Suppression of Th2-Driven Airway Inflammation by Allergen Immunotherapy Is Independent of B Cell and Ig Responses in Mice

Soheila Shirinbak, Yousef A. Taher, Hadi Maazi, +8

The Journal of Immunology

AsthmaInflammatory Lung DiseaseLung InflammationAllergy MedicineImmunology +22

Genetic variance is associated with susceptibility for cigarette smoke-induced DAMP release in mice

Simon D. Pouwels, Alen Faiz, Lisette E. den Boef, +8

American Journal of Physiology-Lung Cellular and Molecular Physiology

Genetic variation associates with susceptibility for cigarette smoke-induced neutrophilia in mice

Simon D. Pouwels, Irene H. Heijink, Uilke Brouwer, +6

American Journal of Physiology-Lung Cellular and Molecular Physiology

AsthmaInflammatory Lung DiseaseLung InflammationGeneticsImmunology +17