Clonal selection in the germinal centre by regulated proliferation and hypermutation

Alexander D. Gitlin, Ziv Shulman, Michel C. Nussenzweig

Nature

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Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine

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Nature Immunology

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HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

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Immunity

Germline PrecursorsImmunologyImmunodominanceImmunologic MechanismHiv Vaccine Design +15

A dynamic T cell–limited checkpoint regulates affinity-dependent B cell entry into the germinal center

Tanja A. Schwickert, Gabriel D. Victora, David Fooksman, +5

The Journal of Experimental Medicine

Rif1 Prevents Resection of DNA Breaks and Promotes Immunoglobulin Class Switching

Michela Di Virgilio, Elsa Callén, Arito Yamane, +11

Science

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Dynamic signaling by T follicular helper cells during germinal center B cell selection

Ziv Shulman, Alexander D. Gitlin, Jason S. Weinstein, +5

Science

Lymphocyte DevelopmentAdaptive Immune SystemT-regulatory CellImmunologyDynamic Signaling +16

T Follicular Helper Cell Dynamics in Germinal Centers

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Science

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Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice

Amelia Escolano, Jon M. Steichen, Pia Dosenovic, +19

Cell

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Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice

Pia Dosenovic, Lotta von Boehmer, Amelia Escolano, +21

Cell

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HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

Joshua A. Horwitz, Ariel Halper-Stromberg, Hugo Mouquet, +17

Proceedings of the National Academy of Sciences