Waldemar Pfrengle

8-(3-(<i>R</i>)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a Highly Potent, Selective, Long-Acting, and Orally Bioavailable DPP-4 Inhibitor for the Treatment of Type 2 Diabetes

Matthias Eckhardt, Elke Langkopf, Michael Mark et al. · Journal of Medicinal Chemistry · 2007 · 281 citations · Full text

Pharmaceutical Science, Xanthine Scaffold, Pharmacotherapy +17

Asymmetric synthesis on carbohydrate templates: stereoselective Ugi-synthesis of .alpha.-amino acid derivatives

Horst Kunz, Waldemar Pfrengle · Journal of the American Chemical Society · 1988 · 168 citations

Enantioselective Synthesis, Bioorganic Chemistry, Engineering +15

Carbohydrates as Chiral Templates: Stereoselective Tandem Mannich‐Michael Reactions for the Synthesis of Piperidine Alkaloids

Horst Kunz, Waldemar Pfrengle · Angewandte Chemie International Edition in English · 1989 · 137 citations

High Yields, Chiral Templates, Engineering +13

Hetero-Diels-Alder reactions on a carbohydrate template: stereoselective synthesis of (S)-anabasin

Waldemar Pfrengle, Horst Kunz · The Journal of Organic Chemistry · 1989 · 111 citations

Molecular Sciences, Bioorganic Chemistry, Engineering +15

Carbohydrates as chiral templates: asymmetric ugi-synthesis of alpha-amino acids using galactosylamines as the chiral matrices

Horst Kunz, Waldemar Pfrengle · Tetrahedron · 1988 · 98 citations

Chiral Templates, Biosynthesis, Alpha-amino Acids +13