Dianne K. Bryce

Negative Allosteric Modulation of the mGluR5 Receptor Reduces Repetitive Behaviors and Rescues Social Deficits in Mouse Models of Autism

Jill L. Silverman, Daniel G. Smith, Stacey J. Sukoff Rizzo et al. · Science Translational Medicine · 2012 · 252 citations · Full text

Pharmacology of CP-99,994; a nonpeptide antagonist of the tachykinin neurokinin-1 receptor.

Stafford McLean, Alan H. Ganong, P A Seymour et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 222 citations

Activity and Distribution of Binding Sites in Brain of a Nonpeptide Substance P (NK ₁ ) Receptor Antagonist

Stafford McLean, Alan H. Ganong, Thomas Seeger et al. · Science · 1991 · 218 citations

Neurotransmitter, Receptor Antagonist, Guinea Pig Brain +18

LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits

Marco A. S. Baptista, Kalpana Merchant, Ted Barrett et al. · Science Translational Medicine · 2020 · 123 citations

The discovery of (2S,3S)-cis-2-(diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine as a novel, nonpeptide substance P antagonist

John Lowe, Susan E. Drozda, R. Michael Snider et al. · Journal of Medicinal Chemistry · 1992 · 107 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Pharmaceutical Chemistry +15