Dimorphic effects of Notch signaling in bone homeostasis

Feyza Engin, Zhenqiang Yao, Tao Yang, +9

Nature Medicine

MechanobiologyDevelopmental BiologySignal TransductionBone Morphogenic ProteinOsteoporosis +6

Dominance of SOX9 function over RUNX2 during skeletogenesis

Guang Zhou, Qiping Zheng, Feyza Engin, +5

Proceedings of the National Academy of Sciences

Runx Gene FamilySox9 FunctionSclerostinGeneticsBone Repair +18

Restoration of the Unfolded Protein Response in Pancreatic β Cells Protects Mice Against Type 1 Diabetes

Feyza Engin, Alena Yermalovich, Truc Nguyen, +5

Science Translational Medicine

Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms

Flora Brozzi, Tarlliza R. Nardelli, Miguel Lopes, +12

Diabetologia

InflammationCytokineDifferent MechanismsAutoimmune DiseaseAutophagy +10

Notch signaling contributes to the pathogenesis of human osteosarcomas

Feyza Engin, Terry Bertin, Ou Ma, +5

Human Molecular Genetics

Tumor BiologyAltered Notch SignalingSignaling PathwayBone Morphogenic ProteinMedicine +13

Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes

Hugo Lee, Yong-Syu Lee, Quincy Eckert Harenda, +10

Cell Metabolism

Signal TransductionMolecular PhysiologyDiabetesDiabetes MellitusSystems Biology +4

Aberrant islet unfolded protein response in type 2 diabetes

Feyza Engin, Truc Nguyen, Alena Yermalovich, +1

Scientific Reports

Adaptation to chronic ER stress enforces pancreatic β-cell plasticity

Chien-Wen Chen, Bo‐Jhih Guan, Mohammed R. Alzahrani, +19

Nature Communications

A hormone complex of FABP4 and nucleoside kinases regulates islet function

Kacey J. Prentice, Jani Saksi, Lauren Robertson, +11

Nature

Islet FunctionSignal TransductionMolecular PhysiologyEndocrine MechanismMolecular Pathway +12

Stress-induced β cell early senescence confers protection against type 1 diabetes

Hugo Lee, Gulcan Semra Sahin, Chien-Wen Chen, +9

Cell Metabolism