Erin E. Pusateri

Blockade of Protein Geranylgeranylation Inhibits Cdk2-Dependent p27^Kip1 Phosphorylation on Thr187 and Accumulates p27^Kip1 in the Nucleus: Implications for Breast Cancer Therapy

Aslamuzzaman Kazi, Adam Carie, Michelle A. Blaskovich et al. · Molecular and Cellular Biology · 2009 · 62 citations · Full text

Medicine, Oncology, Pharmacology +17

Synthesis and evaluation of potent, highly-selective, 3-aryl-piperazinone inhibitors of protein geranylgeranyltransferase-I

Hairuo Peng, Dora Carrico, Van Thai et al. · Organic & Biomolecular Chemistry · 2006 · 52 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Structural Basis for Binding and Selectivity of Antimalarial and Anticancer Ethylenediamine Inhibitors to Protein Farnesyltransferase

Michael A. Hast, Steven Fletcher, Christopher G. Cummings et al. · Chemistry & Biology · 2009 · 37 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Structurally Simple, Potent, <i>Plasmodium</i> Selective Farnesyltransferase Inhibitors That Arrest the Growth of Malaria Parasites

Matthew P. Glenn, Sung-Youn Chang, Carrie Hornéy et al. · Journal of Medicinal Chemistry · 2006 · 34 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure-based design of imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase

Junko Ohkanda, Corey L. Strickland, Michelle A. Blaskovich et al. · Organic & Biomolecular Chemistry · 2006 · 11 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14