Mast cell–derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B

Michele A. Grimbaldeston, Susumu Nakae, Janet Kalesnikoff, +2

Nature Immunology

InflammationUltraviolet BImmunologyContact DermatitisChronic Irradiation +4

Monomeric IgE Stimulates Signaling Pathways in Mast Cells that Lead to Cytokine Production and Cell Survival

Janet Kalesnikoff, Michael Huber, Vivian Lam, +4

Immunity

InflammationCytokine ProductionImmunogeneticsCytokineAllergy +13

LPS-Induced Upregulation of SHIP Is Essential for Endotoxin Tolerance

Laura M. Sly, Michael J. Rauh, Janet Kalesnikoff, +2

Immunity

InflammationEndotoxin ToleranceImmunotoxicologyPathogenesisImmunology +3

SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts

Sunao Takeshita, Noriyuki Namba, Jenny Zhao, +11

Nature Medicine

Bone DiseaseHyper-resorptive OsteoclastsShip-deficient MicePhysiologyIncreased Numbers +7

Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice

Jennifer N. Lilla, Ching‐Cheng Chen, Kaori Mukai, +7

Blood

A Beneficial Role for Immunoglobulin E in Host Defense against Honeybee Venom

Thomas Marichal, Philipp Starkl, Laurent L. Reber, +5

Immunity

AllergyEntomologyImmunologyInnate Immune SystemVenomics +6

Mast Cell-Derived TNF Can Exacerbate Mortality during Severe Bacterial Infections in C57BL/6-Kit Mice

Adrian M. Piliponsky, Ching‐Cheng Chen, Michele A. Grimbaldeston, +6

American Journal Of Pathology

InflammationCytokineMast Cell DisorderPathogenesisImmune Regulation +10

SHIP Negatively Regulates IgE + Antigen-Induced IL-6 Production in Mast Cells by Inhibiting NF-κB Activity

Janet Kalesnikoff, Nicole Baur, Michael Leitges, +4

The Journal of Immunology

Protein Kinase C-δ Is a Negative Regulator of Antigen-Induced Mast Cell Degranulation

Michael Leitges, Kerstin Gimborn, Winfried Elis, +4

Molecular and Cellular Biology

Negative RegulatorMolecular RegulationMast Cell DisorderImmunologyImmune Regulation +18

Evidence questioning cromolyn's effectiveness and selectivity as a ‘mast cell stabilizer' in mice

Tatsuya Oka, Janet Kalesnikoff, Philipp Starkl, +2

Laboratory Investigation

Knockout MouseDevelopmental BiologyMast Cell DisorderMedicineCell Biology +2