Clévio Nóbrega

Silencing Mutant Ataxin-3 Rescues Motor Deficits and Neuropathology in Machado-Joseph Disease Transgenic Mice

Clévio Nóbrega, Isabel Nascimento-Ferreira, Isabel Onofre et al. · PLoS ONE · 2013 · 119 citations · Full text

Genetics, Disease Onset, Disease Gene Identification +18

Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype

Mariana Conceição, Liliana Mendonça, Clévio Nóbrega et al. · Biomaterials · 2015 · 113 citations

Neurodegenerative Diseases, Intravenous Administration, Medicine +9

Silencing ataxin-3 mitigates degeneration in a rat model of Machado–Joseph disease: no role for wild-type ataxin-3?

Sandro Alves, Isabel Nascimento-Ferreira, Noëlle Dufour et al. · Human Molecular Genetics · 2010 · 105 citations · Full text

Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado–Joseph disease

Isabel Nascimento-Ferreira, Clévio Nóbrega, Ana Vasconcelos‐Ferreira et al. · Brain · 2013 · 96 citations · Full text

Genetics, Immunology, Synaptic Signaling +20

Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice

Liliana Mendonça, Clévio Nóbrega, Hirokazu Hirai et al. · Brain · 2014 · 85 citations · Full text

Neurological Disorder, Social Sciences, Neuroregeneration +18