Expansion of HIV-specific T follicular helper cells in chronic HIV infection

Madelene Lindqvist, Jan van Lunzen, Damien Z. Soghoian, +14

Journal of Clinical Investigation

Chronic Hiv InfectionAutoimmune DiseaseHiv Viremia DriveHuman RetrovirusImmunology +12

HIV-Specific Cytolytic CD4 T Cell Responses During Acute HIV Infection Predict Disease Outcome

Damien Z. Soghoian, Heiko Jessen, Michael Flanders, +14

Science Translational Medicine

Durvalumab plus tremelimumab alone or in combination with low-dose or hypofractionated radiotherapy in metastatic non-small-cell lung cancer refractory to previous PD(L)-1 therapy: an open-label, multicentre, randomised, phase 2 trial

Jonathan D. Schoenfeld, Anita Giobbie‐Hurder, Srinika Ranasinghe, +34

The Lancet Oncology

MedicinePrevious PdBronchial NeoplasmImmune Checkpoint InhibitorCancer Treatment +3

HIV-1-Specific Interleukin-21 ⁺ CD4 ⁺ T Cell Responses Contribute to Durable Viral Control through the Modulation of HIV-Specific CD8 ⁺ T Cell Function

Mathieu F. Chevalier, Boris Jülg, Augustine Pyo, +15

Journal of Virology

Differential Restriction of Human Immunodeficiency Virus Type 2 and Simian Immunodeficiency Virus SIVmac by TRIM5α Alleles

Laura M. J. Ylinen, Zuzana Keckesova, Sam J. Wilson, +2

Journal of Virology

GeneticsImmunodeficienciesImmunologyViral PathogenesisDifferential Restriction +15

HIV-Specific CD4 T Cell Responses to Different Viral Proteins Have Discordant Associations with Viral Load and Clinical Outcome

Srinika Ranasinghe, Michael Flanders, Sam Cutler, +8

Journal of Virology

T-regulatory CellImmunologyImmunodominanceAntigen ProcessingCd4 T Cell Responses +17

Association of HLA-DRB1–restricted CD4+ T cell responses with HIV immune control

Srinika Ranasinghe, Sam Cutler, Isaiah Davis, +15

Nature Medicine

A Randomized Trial of Combined PD-L1 and CTLA-4 Inhibition with Targeted Low-Dose or Hypofractionated Radiation for Patients with Metastatic Colorectal Cancer

Arta M. Monjazeb, Anita Giobbie‐Hurder, Ana Lako, +31

Clinical Cancer Research

Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion

Srinika Ranasinghe, Pedro A. Lamothe, Damien Z. Soghoian, +19

Immunity

Multilayered Defense in HLA-B51–Associated HIV Viral Control

Yonghong Zhang, Yanchun Peng, Huiping Yan, +19

The Journal of Immunology

Epitope SequencingAutoimmune DiseaseHuman RetrovirusGeneticsHla Immunogenetics +12