Marco Nooteboom

Clonal Expansion of Early to Mid-Life Mitochondrial DNA Point Mutations Drives Mitochondrial Dysfunction during Human Ageing

Laura C. Greaves, Marco Nooteboom, Joanna L. Elson et al. · PLoS Genetics · 2014 · 171 citations · Full text

A mutation in the FAM36A gene, the human ortholog of COX20, impairs cytochrome c oxidase assembly and is associated with ataxia and muscle hypotonia

Radek Szklarczyk, Bas F.J. Wanschers, Leo Nijtmans et al. · Human Molecular Genetics · 2012 · 91 citations · Full text

Genetics, Molecular Biology, Pathology +20

Comparison of Mitochondrial Mutation Spectra in Ageing Human Colonic Epithelium and Disease: Absence of Evidence for Purifying Selection in Somatic Mitochondrial DNA Point Mutations

Laura C. Greaves, Joanna L. Elson, Marco Nooteboom et al. · PLoS Genetics · 2012 · 73 citations · Full text

Somatic Variant, Aging, Mitochondrial Function +14

Sustained accumulation of prelamin A and depletion of lamin A/C both cause oxidative stress and mitochondrial dysfunction but induce different cell fates

Tom Sieprath, Tobias Corne, Marco Nooteboom et al. · Nucleus · 2015 · 71 citations · Full text

Mitochondrial Dysfunction, Nuclear Lamina, Lipid Peroxidation +18

BOLA1 Is an Aerobic Protein That Prevents Mitochondrial Morphology Changes Induced by Glutathione Depletion

Peter H.G.M. Willems, Bas F.J. Wanschers, J.J. Esseling et al. · Antioxidants and Redox Signaling · 2012 · 60 citations · Full text