Rolf Beume

In Vivo Efficacy in Airway Disease Models of Roflumilast, a Novel Orally Active PDE4 Inhibitor

Daniela S. Bundschuh, Manfrid Eltze, Johannes Barsig et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 237 citations

Roflumilast Fully Prevents Emphysema in Mice Chronically Exposed to Cigarette Smoke

Piero A. Martorana, Rolf Beume, Monica Lucattelli et al. · American Journal of Respiratory and Critical Care Medicine · 2005 · 192 citations

Inhibition of Inflammation and Remodeling by Roflumilast and Dexamethasone in Murine Chronic Asthma

Rakesh Kumar, Cristan Herbert, Paul S. Thomas et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 148 citations

Roflumilast N‐oxide, a PDE4 inhibitor, improves cilia motility and ciliated human bronchial epithelial cells compromised by cigarette smoke<i>in vitro</i>

Javier Milara, M Armengot, P Bañuls et al. · British Journal of Pharmacology · 2012 · 80 citations · Full text

The glucose-lowering effects of the PDE4 inhibitors roflumilast and roflumilast-N-oxide in db/db mice

S. Vollert, N. Kaessner, Anke Heuser et al. · Diabetologia · 2012 · 63 citations

Pde4 Inhibitors, Glucose-lowering Effects, Biochemistry +7