LTRPC2 Ca2+-Permeable Channel Activated by Changes in Redox Status Confers Susceptibility to Cell Death

Yuji Hara, Minoru Wakamori, Masakazu Ishii, +12

Molecular Cell

Ltrpc2 Ca2+-permeable ChannelCell PhysiologyRedox SignalingSignal TransductionPhysiology +8

TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration

Shinichiro Yamamoto, Shunichi Shimizu, Shigeki Kiyonaka, +14

Nature Medicine

InflammationInflammatory Neutrophil InfiltrationCytokineMolecular PhysiologySignal Transduction +10

The Transient Receptor Potential Protein Homologue TRP6 Is the Essential Component of Vascular α₁-Adrenoceptor–Activated Ca²⁺-Permeable Cation Channel

Ryuji Inoue, Takaharu Okada, Hitoshi Onoue, +5

Circulation Research

Nitric oxide activates TRP channels by cysteine S-nitrosylation

Takashi Yoshida, Ryuji Inoue, Takashi Morii, +7

Nature Chemical Biology

Molecular PhysiologySignal TransductionBiochemistryReactive Nitrogen SpecieNitric Oxide +5

TRPM2 activation by cyclic ADP‐ribose at body temperature is involved in insulin secretion

Kazuya Togashi, Yuji Hara, Tomoko Tominaga, +4

The EMBO Journal

Mutations in EFHC1 cause juvenile myoclonic epilepsy

Toshimitsu Suzuki, Antonio V. Delgado‐Escueta, Kripamoy Aguan, +25

Nature Genetics

Disease Gene IdentificationGeneticsNeuroscienceGenetic Disorder

Dystroglycan Function Requires Xylosyl- and Glucuronyltransferase Activities of LARGE

Kei‐ichiro Inamori, Takako Yoshida‐Moriguchi, Yuji Hara, +3

Science

A Dystroglycan Mutation Associated with Limb-Girdle Muscular Dystrophy

Yuji Hara, Burcu Balcı-Hayta, Takako Yoshida‐Moriguchi, +15

New England Journal of Medicine

GlycobiologyPathologyCellular PhysiologyMendelian DisorderSkeletal Muscle +19

RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels

Shigeki Kiyonaka, Minoru Wakamori, Takafumi Miki, +12

Nature Neuroscience

Synaptic PlasticityMolecular NeuroscienceSignal TransductionMolecular PhysiologyPhysiology +12

A Critical Role of TRPM2 in Neuronal Cell Death by Hydrogen Peroxide

Shuji Kaneko, Seiko Kawakami, Yuji Hara, +8

Journal of Pharmacological Sciences