Acinar cell NLRP3 inflammasome and gasdermin D (GSDMD) activation mediates pyroptosis and systemic inflammation in acute pancreatitis

Lin Gao, Xiaowu Dong, Weijuan Gong, +16

British Journal of Pharmacology

IL22RA1/STAT3 Signaling Promotes Stemness and Tumorigenicity in Pancreatic Cancer

Weizhi He, Jinghua Wu, Juanjuan Shi, +11

Cancer Research

THZ1 reveals CDK7-dependent transcriptional addictions in pancreatic cancer

Ping Lu, Jing Geng, Lei Zhang, +10

Oncogene

Pancreatic CancerMedicineCancer BiologyCell BiologyCell Signaling +1

Loss of Setd2 promotes Kras-induced acinar-to-ductal metaplasia and epithelia–mesenchymal transition during pancreatic carcinogenesis

Ningning Niu, Ping Lu, Yan-Lin Yang, +13

Gut

Tumor Cell‐Intrinsic SETD2 Deficiency Reprograms Neutrophils to Foster Immune Escape in Pancreatic Tumorigenesis

Ningning Niu, Xuqing Shen, Li Zhang, +13

Advanced Science

PPARα induces cell apoptosis by destructing Bcl2

Jiaming Gao, Qian Liu, Ying Xu, +8

Oncotarget

TRIM50 acts as a novel Src suppressor and inhibits ovarian cancer progression

Yumin Qiu, Peishu Liu, Xiaomin Ma, +11

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Novel Src SuppressorMedicineGynecologyCancer Cell BiologyCancer Biology +7

<p>Akt/mTOR-Mediated Autophagy Confers Resistance To BET Inhibitor JQ1 In Ovarian Cancer</p>

Wenqing Luan, Yingxin Pang, Rui Li, +6

OncoTargets and Therapy

PPARδ promotes tumor progression via activation of Glut1 and SLC1-A5 transcription

Wenbo Zhang, Ying Xu, Qinggang Xu, +3

Carcinogenesis

Tumor ProgressionMetabolic RemodelingCancer BiologyTumor BiologyTranscriptional Regulation +21

EGFR/MDM2 signaling promotes NF-κB activation via PPARγ degradation

Ying Xu, Jianhua Jin, Wenbo Zhang, +8

Carcinogenesis