Tangui Le Guen

Human RTEL1 deficiency causes Hoyeraal–Hreidarsson syndrome with short telomeres and genome instability

Tangui Le Guen, Laurent Jullien, Fabien Touzot et al. · Human Molecular Genetics · 2013 · 191 citations · Full text

An in vivo genetic reversion highlights the crucial role of Myb-Like, SWIRM, and MPN domains 1 (MYSM1) in human hematopoiesis and lymphocyte differentiation

Tangui Le Guen, Fabien Touzot, Isabelle André‐Schmutz et al. · Journal of Allergy and Clinical Immunology · 2015 · 110 citations

Hematological Malignancy, Immunogenetics, Medicine +8

The Cohesin Complex Prevents the End Joining of Distant DNA Double-Strand Ends

Camille Gelot, Josée Guirouilh‐Barbat, Tangui Le Guen et al. · Molecular Cell · 2015 · 91 citations · Full text

Chromatin, Genome Instability, Nucleic Acid Chemistry +9

Primary Microcephaly, Impaired DNA Replication, and Genomic Instability Caused by Compound Heterozygous<i>ATR</i>Mutations

Houda Benhelli‐Mokrani, Laetitia Gaillard, Patricia Biasutto et al. · Human Mutation · 2012 · 55 citations

Genetics, Genomic Mechanism, Molecular Genetics +17

Heterogeneous telomere defects in patients with severe forms of dyskeratosis congenita

Fabien Touzot, Laetitia Gaillard, Nadia Vasquez et al. · Journal of Allergy and Clinical Immunology · 2011 · 41 citations

Genetic Disorder, Medicine, Dyskeratosis Congenita +3