Graham R. Cumming

The Discovery of Polo-Like Kinase 4 Inhibitors: Identification of (1<i>R</i>,2<i>S</i>)-2-(3-((<i>E</i>)-4-(((<i>cis</i>)-2,6-Dimethylmorpholino)methyl)styryl)-1<i>H</i>-indazol-6-yl)-5′-methoxyspiro[cyclopropane-1,3′-indolin]-2′-one (CFI-400945) as a Potent, Orally Active Antitumor Agent

Peter B. Sampson, Yong Liu, Bryan Forrest et al. · Journal of Medicinal Chemistry · 2014 · 171 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Structural insights into probe-dependent positive allosterism of the GLP-1 receptor

Ana B. Bueno, Bingfa Sun, Francis S. Willard et al. · Nature Chemical Biology · 2020 · 95 citations

Life Sciences, Biochemistry, Physiology +16

Photochemically Mediated Ring Expansion of Indoles and Pyrroles with Chlorodiazirines: Synthetic Methodology and Thermal Hazard Assessment

Ben W. Joynson, Graham R. Cumming, Liam T. Ball · Angewandte Chemie International Edition · 2023 · 88 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +17

Electrochemical Nickel-Catalyzed C(sp³)–C(sp³) Cross-Coupling of Alkyl Halides with Alkyl Tosylates

Malek Y. S. Ibrahim, Graham R. Cumming, Raquel González de Vega et al. · Journal of the American Chemical Society · 2023 · 58 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +15

Asymmetric Catalytic Hydrogenolysis of ArylHalide Bonds in Fused Arene Chromium and Ruthenium Complexes

Audrey Mercier, Xavier Urbaneja, Wee Chuan Yeo et al. · Chemistry - A European Journal · 2010 · 52 citations

Natural Sciences, Chemistry, Catalysis +16