Shih-Min A. Huang

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

Shih-Min A. Huang, Yuji Mishina, Shanming Liu et al. · Nature · 2009 · 2.1K citations

Tankyrase Inhibition, Signal Transduction, Signaling Pathway +7

PIM inhibitors target CD25-positive AML cells through concomitant suppression of STAT5 activation and degradation of MYC oncogene

Zhuyan Guo, Anlai Wang, Weidong Zhang et al. · Blood · 2014 · 43 citations · Full text

Combination of PIM and JAK2 inhibitors synergistically suppresses cell proliferation and overcomes drug resistance of myeloproliferative neoplasms

Shih-Min A. Huang, Anlai Wang, Rita Greco et al. · Oncotarget · 2014 · 31 citations · Full text

Cell Proliferation, Tumor Biology, Myeloid Neoplasia +18

Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches

Qiang Gao, I. Mechin, Nayantara Kothari et al. · Journal of Biological Chemistry · 2013 · 30 citations · Full text

Cancer Dependence, Structural Approaches, Medicine +9