Joseph Barbosa

Modulation of Receptor and Receptor Subtype Affinities Using Diastereomeric and Enantiomeric Monosaccharide Scaffolds as a Means to Structural and Biological Diversity. A New Route to Ether Synthesis

Ralph Hirschmann, John Hynes, Maria A. Cichy-Knight et al. · Journal of Medicinal Chemistry · 1998 · 108 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure-based design of potent and selective inhibitors of collagenase-3 (MMP-13)

Soong‐Hoon Kim, Andrew T. Pudzianowski, Kenneth J. Leavitt et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 94 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Inhibition of Sphingosine-1-Phosphate Lyase for the Treatment of Autoimmune Disorders

Jeffrey T. Bagdanoff, Michael S. Donoviel, Amr Nouraldeen et al. · Journal of Medicinal Chemistry · 2009 · 76 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +15

Total Synthesis of (+)-Calyculin A and (−)-Calyculin B:  Asymmetric Synthesis of the C(9−25) Spiroketal Dipropionate Subunit

Amos B. Smith, Gregory K. Friestad, Joseph Barbosa et al. · Journal of the American Chemical Society · 1999 · 74 citations

Natural Sciences, Biochemistry, Chemistry +16

Total Synthesis of (+)-Calyculin A and (−)-Calyculin B:  Cyanotetraene Construction, Asymmetric Synthesis of the C(26−37) Oxazole, Fragment Assembly, and Final Elaboration

Amos B. Smith, Gregory K. Friestad, Joseph Barbosa et al. · Journal of the American Chemical Society · 1999 · 69 citations

Pharmacy, Chemistry, Carbohydrate Chemistry +12