David M. Reynolds

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

Christelle Peyron, Juliette Faraco, William M. Rogers et al. · Nature Medicine · 2000 · 2.1K citations

Life Sciences, Neurology, Neuroscience +13

<b> <i>PKD2</i> </b> , a Gene for Polycystic Kidney Disease That Encodes an Integral Membrane Protein

Toshio Mochizuki, Guanqing Wu, Tomohito Hayashi et al. · Science · 1996 · 1.4K citations

Medicine, Genetics, Molecular Genetics +17

Somatic Inactivation of Pkd2 Results in Polycystic Kidney Disease

Guanqing Wu, Vivette D. D’Agati, Yiqiang Cai et al. · Cell · 1998 · 572 citations · Full text

Medicine, Genetics, Molecular Genetics +15

Activin A Efficiently Specifies Definitive Endoderm from Human Embryonic Stem Cells Only When Phosphatidylinositol 3-Kinase Signaling Is Suppressed

Amanda B. McLean, Kevin A. D’Amour, Karen L. Jones et al. · Stem Cells · 2007 · 475 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +17

Signaling Network Crosstalk in Human Pluripotent Cells: A Smad2/3-Regulated Switch that Controls the Balance between Self-Renewal and Differentiation

Amar M. Singh, David M. Reynolds, Timothy S. Cliff et al. · Cell stem cell · 2012 · 362 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16