Nuclear Receptor-Dependent Bile Acid Signaling Is Required for Normal Liver Regeneration

Wendong Huang, Ke Ma, Jun Zhang, +6

Science

Fatty Liver DiseaseHepatotoxicityBiliary DisorderMetabolismCell Signaling +17

Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease

Bingning Dong, Pradip Saha, Wendong Huang, +8

Proceedings of the National Academy of Sciences

PathologyFatty Liver DiseaseInsulin SignalingOxidative StressGastrointestinal Peptide Hormone +18

MicroRNA-26a regulates insulin sensitivity and metabolism of glucose and lipids

Xianghui Fu, Bingning Dong, Yan Tian, +11

Journal of Clinical Investigation

PathologyFatty Liver DiseaseInsulin SignalingObesityMetabolic Syndrome +18

Vertical sleeve gastrectomy activates GPBAR‐1/TGR5 to sustain weight loss, improve fatty liver, and remit insulin resistance in mice

Lili Ding, Kyle M. Sousa, Lihua Jin, +14

Hepatology

Vitamin D Receptor Activation in Liver Macrophages Ameliorates Hepatic Inflammation, Steatosis, and Insulin Resistance in Mice

Bingning Dong, Ying Zhou, Wei Wang, +11

Hepatology

SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein

Chong Geng, Salma Kaochar, M. Li, +13

Oncogene

Transcriptional RegulationUrologySignal TransductionEpithelial Cell ProliferationSignaling Pathway +8

Molecular mechanisms in MASLD/MASH-related HCC

Xiaobo Wang, Liang Zhang, Bingning Dong

Hepatology

Aldo-keto ReductaseImmunologyMolecular BiologyPathologySystemic Therapies +21

MAPK4 overexpression promotes tumor progression via noncanonical activation of AKT/mTOR signaling

Wei Wang, Tao Shen, Bingning Dong, +8

Journal of Clinical Investigation

Tumor ProgressionCancer BiologyMapk4 OverexpressionTumor BiologySignaling Pathway +16

Activating CAR and β-catenin induces uncontrolled liver growth and tumorigenesis

Bingning Dong, Ju‐Seog Lee, Yun‐Yong Park, +5

Nature Communications

Significance and Mechanism of CYP7a1 Gene Regulation during the Acute Phase of Liver Regeneration

Lisheng Zhang, Xiongfei Huang, Zhipeng Meng, +4

Molecular Endocrinology

CholangiopathiesAcute PhaseCyp7a1 Gene RegulationBile AcidHepatotoxicity +15