Toshihide Shibazaki

KGA-2727, a Novel Selective Inhibitor of a High-Affinity Sodium Glucose Cotransporter (SGLT1), Exhibits Antidiabetic Efficacy in Rodent Models

Toshihide Shibazaki, Masaki Tomae, Yukiko Ishikawa-Takemura et al. · Journal of Pharmacology and Experimental Therapeutics · 2012 · 81 citations

Decrease in the density of t-tubular L-type Ca²⁺ channel currents in failing ventricular myocytes

Miwa Horiuchi‐Hirose, Toshihide Kashihara, Tsutomu Nakada et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2010 · 39 citations

Structure–activity relationship studies of 4-benzyl-1H-pyrazol-3-yl β-d-glucopyranoside derivatives as potent and selective sodium glucose co-transporter 1 (SGLT1) inhibitors with therapeutic activity on postprandial hyperglycemia

Nobuhiko Fushimi, Hideki Fujikura, Hiroaki Shiohara et al. · Bioorganic & Medicinal Chemistry · 2012 · 19 citations · Full text

Pharmaceutical Science, Biochemistry, Medicine +9

Phlorizin Prevents Electrically-Induced Ventricular Tachyarrhythmia during Ischemia in Langendorff-Perfused Guinea-Pig Hearts

Masamichi Hirose, Toshihide Shibazaki, Tsutomu Nakada et al. · Biological and Pharmaceutical Bulletin · 2014 · 15 citations · Full text

Cardiac Muscle, Heart Failure, Impulse Conduction +15

Design, synthesis, and structure–activity relationships of a series of 4-benzyl-5-isopropyl-1H-pyrazol-3-yl β-d-glycopyranosides substituted with novel hydrophilic groups as highly potent inhibitors of sodium glucose co-transporter 1 (SGLT1)

Nobuhiko Fushimi, Hirotaka Teranishi, Kazuo Shimizu et al. · Bioorganic & Medicinal Chemistry · 2012 · 15 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +11