Physical interaction of junctophilin and the Ca _V 1.1 C terminus is crucial for skeletal muscle contraction

Tsutomu Nakada, Toshihide Kashihara, Masatoshi Komatsu, +3

Proceedings of the National Academy of Sciences

Nampt Potentiates Antioxidant Defense in Diabetic Cardiomyopathy

Shinichi Oka, Jaemin Byun, Chun-Yang Huang, +14

Circulation Research

Visual LanguageCardiovascular DiseaseMedicineLipid PeroxidationPhysiology +8

Decrease in the density of t-tubular L-type Ca²⁺ channel currents in failing ventricular myocytes

Miwa Horiuchi‐Hirose, Toshihide Kashihara, Tsutomu Nakada, +11

American Journal of Physiology-Heart and Circulatory Physiology

Increased predominance of the matured ventricular subtype in embryonic stem cell-derived cardiomyocytes in vivo

Hajime Ichimura, Shin Kadota, Toshihide Kashihara, +11

Scientific Reports

Transplantation of adipose tissue-derived stem cells improves cardiac contractile function and electrical stability in a rat myocardial infarction model

Milan Gautam, Daiki Fujita, Kazuhiro Kimura, +8

Journal of Molecular and Cellular Cardiology

Regenerative MedicineInduced Pluripotent Stem CellCardiac Contractile FunctionElectrical StabilityMedicine +10

Angiotensin II activates Ca_V1.2 Ca²⁺ channels through β‐arrestin2 and casein kinase 2 in mouse immature cardiomyocytes

Toshihide Kashihara, Tsutomu Nakada, Katsuhiko Kojima, +2

The Journal of Physiology

Thioredoxin-1 maintains mitochondrial function via mechanistic target of rapamycin signalling in the heart

Shinichi Oka, Adave Chin, Jiyeon Park, +16

Cardiovascular Research

Proteomic analysis of mitochondrial biogenesis in cardiomyocytes differentiated from human induced pluripotent stem cells

Sundararajan Venkatesh, Erdene Baljinnyam, Mingming Tong, +10

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Cardiac Progenitor CellsRetinoblastoma ProteinMitochondrial BiologyMetabolic RemodelingOxidative Stress +21

Novel Regulation of Cardiac Metabolism and Homeostasis by the Adrenomedullin-Receptor Activity-Modifying Protein 2 System

Takahiro Yoshizawa, Takayuki Sakurai, Akiko Kamiyoshi, +19

Hypertension

Cardiac MuscleHeart FailureHomeostatic MechanismCardiac Progenitor CellsCardiac Regeneration +25

β-Arrestin–Biased AT1 Agonist TRV027 Causes a Neonatal-Specific Sustained Positive Inotropic Effect Without Increasing Heart Rate

Toshihide Kashihara, Hiroyuki Kawagishi, Tsutomu Nakada, +7

JACC Basic to Translational Science