Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape

Parisha P. Shah, Greg Donahue, Gabriel Otte, +10

Genes & Development

Histone ModificationsEpigenetic ChangeEpigeneticsTumor BiologyCell Regulation +19

The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila

Nan Liu, Michael Landreh, Kajia Cao, +6

Nature

Molecular NeuroscienceLongevityGeneticsMicrorna Mir-34 ModulatesSmall Rna +4

BCL2 Translocation Defines a Unique Tumor Subset within the Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma

Javeed Iqbal, Warren G. Sanger, Douglas E. Horsman, +25

American Journal Of Pathology

Unique Tumor SubsetTumor BiologyLymphoid NeoplasiaHematological MalignancyMedicine +6

H3K36 methylation promotes longevity by enhancing transcriptional fidelity

Payel Sen, Weiwei Dang, Greg Donahue, +17

Genes & Development

Histone ModificationsAgingEpigenetic ChangeGeneticsEpigenetics +16

Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies

Javeed Iqbal, Can Küçük, Ronald J. deLeeuw, +14

Leukemia

Cancer ImmunosurveillanceTumor GrowthImmunologyCancer GenomicsNatural Killer-cell Malignancies +6

Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential

Jay E. Johnson, Kajia Cao, Paul Ryvkin, +2

Nucleic Acids Research

Genome-Wide Double-Stranded RNA Sequencing Reveals the Functional Significance of Base-Paired RNAs in Arabidopsis

Qi Zheng, Paul Ryvkin, Fan Li, +6

PLoS Genetics

Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease

Steven E. Arnold, Natalia Louneva, Kajia Cao, +9

Neurobiology of Aging

Synaptic PlasticityCognitive ScienceAlzheimer's DiseaseCellular NeurobiologyBrain Function +12

Association of G-quadruplex forming sequences with human mtDNA deletion breakpoints

Dawei Dong, Filipe Pereira, Steven P. Barrett, +6

BMC Genomics

Inactivation of Yeast Isw2 Chromatin Remodeling Enzyme Mimics Longevity Effect of Calorie Restriction via Induction of Genotoxic Stress Response

Weiwei Dang, George L. Sutphin, Jean Dorsey, +15

Cell Metabolism

Caloric RestrictionChromatinLifespan ExtensionCalorie RestrictionChromatin Remodeling +11