Steven W. Louie

From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)

Yuan Cheng, Ted Judd, Michael D. Bartberger et al. · Journal of Medicinal Chemistry · 2011 · 136 citations · Full text

Effects of fibrates on human organic anion-transporting polypeptide 1B1-, multidrug resistance protein 2- and P-glycoprotein-mediated transport

Mami Yamazaki, B. LI, Steven W. Louie et al. · Xenobiotica · 2005 · 95 citations

Structure- and Property-Based Design of Aminooxazoline Xanthenes as Selective, Orally Efficacious, and CNS Penetrable BACE Inhibitors for the Treatment of Alzheimer’s Disease

Hongbing Huang, Daniel S. La, Alan C. Cheng et al. · Journal of Medicinal Chemistry · 2012 · 66 citations · Full text

Pharmaceutical Science, Peptide Science, Pharmacotherapy +21

Design and Preparation of a Potent Series of Hydroxyethylamine Containing β-Secretase Inhibitors That Demonstrate Robust Reduction of Central β-Amyloid

Matthew M. Weiss, Toni Williamson, Safura Babu‐Khan et al. · Journal of Medicinal Chemistry · 2012 · 63 citations · Full text

Design and Synthesis of Potent, Orally Efficacious Hydroxyethylamine Derived β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors

Thomas A. Dineen, Matthew M. Weiss, Toni Williamson et al. · Journal of Medicinal Chemistry · 2012 · 41 citations · Full text

Pharmacotherapy, Chemical Biology, Pharmaceutical Chemistry +19