Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor

Jan Terje Andersen, Bjørn Dalhus, Jason Cameron, +8

Nature Communications

Extending Serum Half-life of Albumin by Engineering Neonatal Fc Receptor (FcRn) Binding

Jan Terje Andersen, Bjørn Dalhus, Dorthe Viuff, +14

Journal of Biological Chemistry

Posttranslational Modification of Gluten Shapes TCR Usage in Celiac Disease

Shuo‐Wang Qiao, Melinda Ráki, Kristin Støen Gunnarsen, +4

The Journal of Immunology

Gluten AgMolecular ImmunologyTcr Sequence AnalysisAllergyAutoimmune Disease +11

Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease

Lene S. Høydahl, Lisa Richter, Rahel Frick, +15

Gastroenterology

InflammationAutoimmune DiseaseMucosal ImmunologyCeliac DiseaseImmunology +9

Fc Engineering of Human IgG1 for Altered Binding to the Neonatal Fc Receptor Affects Fc Effector Functions

Algirdas Grevys, Malin Bern, Stian Foss, +7

The Journal of Immunology

ImmunologyImmune RegulationImmunologic MechanismHuman Igg1Cellular Physiology +18

Interaction with Both Domain I and III of Albumin Is Required for Optimal pH-dependent Binding to the Neonatal Fc Receptor (FcRn)

Kine Marita Knudsen Sand, Malin Bern, Jeannette Nilsen, +7

Journal of Biological Chemistry

Signal TransductionSignaling PathwayCell SignalingReceptor (Biochemistry)Optimal Ph-dependent Binding +8

Chimeric Anti-CD14 IGG2/4 Hybrid Antibodies for Therapeutic Intervention in Pig and Human Models of Inflammation

Corinna Lau, Kristin Støen Gunnarsen, Lene S. Høydahl, +12

The Journal of Immunology

A high-affinity human TCR-like antibody detects celiac disease gluten peptide–MHC complexes and inhibits T cell activation

Rahel Frick, Lene S. Høydahl, Jan Petersen, +17

Science Immunology

Chaperone-assisted thermostability engineering of a soluble T cell receptor using phage display

Kristin Støen Gunnarsen, Solveig Gunn Kristinsson, Sune Justesen, +5

Scientific Reports

Periplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA

Kristin Støen Gunnarsen, Elin Lunde, Per Eugen Kristiansen, +3

BMC Biotechnology