John Zhou

Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial

E. Antonio Chiocca, Rimas V. Lukas, Isaac H. Solomon et al. · Science Translational Medicine · 2019 · 266 citations · Full text

Medicine, Oncology, Pharmacology +17

Structure−Function Engineering of Interferon-β-1b for Improving Stability, Solubility, Potency, Immunogenicity, and Pharmacokinetic Properties by Site-Selective Mono-PEGylation

Amartya Basu, Karen Yang, Maoliang Wang et al. · Bioconjugate Chemistry · 2006 · 214 citations

Pharmacy, Bioengineering, Pharmacokinetics +17

Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance

Neeraj Singh, Brati Das, John Zhou et al. · Science Advances · 2022 · 83 citations · Full text

Medicine, Neurology, Neuroscience +14

BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1

Neeraj Singh, Marc Benoit, John Zhou et al. · Science Advances · 2022 · 66 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Releasable PEGylation of Mesothelin Targeted Immunotoxin SS1P Achieves Single Dosage Complete Regression of a Human Carcinoma in Mice

David Filpula, Karen Yang, Amartya Basu et al. · Bioconjugate Chemistry · 2007 · 44 citations

Medicine, Oncology, Pharmacology +17