Jack T. Lin

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model

Elizabeth E. Spangenberg, Paul Severson, Lindsay A. Hohsfield et al. · Nature Communications · 2019 · 894 citations · Full text

Exploiting a natural conformational switch to engineer an interleukin-2 ‘superkine’

Aron M. Levin, D.L. Bates, Aaron M. Ring et al. · Nature · 2012 · 538 citations · Full text

Inflammation, Cytokine, Signal Transduction +10

TGF-β1 Uses Distinct Mechanisms to Inhibit IFN-γ Expression in CD4+ T Cells at Priming and at Recall: Differential Involvement of Stat4 and T-bet

Jack T. Lin, Stacey L. Martin, Luxi Xia et al. · The Journal of Immunology · 2005 · 161 citations · Full text

Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion

Roch Houot, Matthew J. Goldstein, Holbrook E. Kohrt et al. · Blood · 2009 · 134 citations · Full text

Activation of the Anticancer Prodrugs Cyclophosphamide and Ifosfamide: Identification of Cytochrome P450 2B Enzymes and Site-Specific Mutants with Improved Enzyme Kinetics

Chong-Sheng Chen, Jack T. Lin, Kendrick A. Goss et al. · Molecular Pharmacology · 2004 · 99 citations