Jonathan Mannion

An innate IL-25–ILC2–MDSC axis creates a cancer-permissive microenvironment for <i>Apc</i> mutation–driven intestinal tumorigenesis

Eric Jou, Noé Rodríguez‐Rodríguez, Ana-Carolina F. Ferreira et al. · Science Immunology · 2022 · 76 citations · Full text

A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death

Jonathan Mannion, Valentina Gifford, Benjamin R. Bellenie et al. · Immunity · 2024 · 63 citations · Full text

An αvβ3 integrin checkpoint is critical for efficient TH2 cell cytokine polarization and potentiation of antigen-specific immunity

Aydan C. H. Szeto, Ana C. F. Ferreira, Jonathan Mannion et al. · Nature Immunology · 2022 · 35 citations · Full text

Adaptive Immune System, αVβ3 Integrin Checkpoint, Antigen-specific Immunity +9

Mef2d potentiates type-2 immune responses and allergic lung inflammation

Aydan C. H. Szeto, Paula A. Clark, Ana C. F. Ferreira et al. · Science · 2024 · 24 citations · Full text

Asthma, Inflammatory Lung Disease, Lung Inflammation +18

Novel biochemical, structural, and systems insights into inflammatory signaling revealed by contextual interaction proteomics

Rodolfo Ciuffa, Federico Uliana, Jonathan Mannion et al. · Proceedings of the National Academy of Sciences · 2022 · 16 citations · Full text

Immunology, Molecular Biology, Inflammation +23