The role of platelets in mediating a response to human influenza infection

Milka Koupenova, Heather A. Corkrey, Olga Vitseva, +10

Nature Communications

Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration

Amine Meliani, Florence Boisgérault, Romain Hardet, +17

Nature Communications

Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication

Marco Gargaro, Giulia Scalisi, Giorgia Manni, +27

Immunity

Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation

Giada Mondanelli, Alice Coletti, Francesco Greco, +28

Proceedings of the National Academy of Sciences

RhoA signaling through platelet P2Y1 receptor controls leukocyte recruitment in allergic mice

Richard T. Amison, Stefania Momi, Abigail Morris, +5

Journal of Allergy and Clinical Immunology

InflammationMolecular ImmunologyMolecular PhysiologyAllergySignal Transduction +8

Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells

Marco Gargaro, Carmine Vacca, Serena Massari, +20

Frontiers in Immunology

3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine

Cristina C. Clement, Angelo D’Alessandro, Sangeetha Thangaswamy, +31

Nature Communications

Pharmacologic Induction of Endotoxin Tolerance in Dendritic Cells by L-Kynurenine

Giorgia Manni, Giada Mondanelli, Giulia Scalisi, +8

Frontiers in Immunology

Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation

Andrea Astolfi, Mark Kudolo, José Brea, +14

European Journal of Medicinal Chemistry

Silico ScreeningDrug TargetMedicineRational Drug DesignVitro Validation +7

S1P promotes migration, differentiation and immune regulatory activity in amniotic-fluid–derived stem cells

Rita Romani, Giorgia Manni, Chiara Donati, +14

European Journal of Pharmacology