Joana Magalhães

Endoperoxide-8-aminoquinoline hybrids as dual-stage antimalarial agents with enhanced metabolic stability

Rita Capela, Joana Magalhães, Daniela Miranda et al. · European Journal of Medicinal Chemistry · 2018 · 32 citations

Biochemistry, Antiparasitic Agent, Medicine +4

Inhibition of Nonessential Bacterial Targets: Discovery of a Novel Serine <i>O</i>-Acetyltransferase Inhibitor

Joana Magalhães, Nina Franko, Samanta Raboni et al. · ACS Medicinal Chemistry Letters · 2020 · 26 citations · Full text

Investigational Studies on a Hit Compound Cyclopropane–Carboxylic Acid Derivative Targeting <i>O</i>-Acetylserine Sulfhydrylase as a Colistin Adjuvant

Giannamaria Annunziato, Costanza Spadini, Nina Franko et al. · ACS Infectious Diseases · 2021 · 26 citations

Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of<i>O</i>-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR

Giannamaria Annunziato, Marco Pieroni, Roberto Benoni et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2016 · 24 citations · Full text

New Tools, Saturation Transfer Difference, Molecular Sciences +15

Discovery of novel fragments inhibiting O-acetylserine sulphhydrylase by combining scaffold hopping and ligand–based drug design

Joana Magalhães, Nina Franko, Giannamaria Annunziato et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2018 · 22 citations · Full text

Cysteine Biosynthesis, Antimicrobial Chemotherapy, Medicinal Chemistry +17