Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis

Ting Wang, Daniele M. Gilkes, Naoharu Takano, +6

Proceedings of the National Academy of Sciences

RETRACTED: Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells

Debangshu Samanta, Daniele M. Gilkes, Pallavi Chaturvedi, +2

Proceedings of the National Academy of Sciences

HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells

Huimin Zhang, Haiquan Lu, Lisha Xiang, +6

Proceedings of the National Academy of Sciences

Cd47 GeneBreast OncologyCd47 ExpressionCell RegulationMedicine +10

Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype

Haiquan Lu, Debangshu Samanta, Lisha Xiang, +5

Proceedings of the National Academy of Sciences

Copper ChelationBreast OncologyChemoprevention StrategyCancer BiologyTumor Biology +14

Glutaminase 1 expression in colorectal cancer cells is induced by hypoxia and required for tumor growth, invasion, and metastatic colonization

Lisha Xiang, Jun Mou, Bin Shao, +5

Cell Death and Disease

PathologyCancer BiologyTumor BiologyOxidative StressOncology +15

RETRACTED: Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells

Daniele M. Gilkes, Lisha Xiang, Sun Joo Lee, +4

Proceedings of the National Academy of Sciences

Hypoxia-inducible FactorsCytoskeletonCancer BiologyTumor BiologyBreast Cancer Progression +16

Hypoxia Selectively Enhances Integrin α5β1 Receptor Expression in Breast Cancer to Promote Metastasis

Julia A. Ju, Inês Godet, I. Chae Ye, +10

Molecular Cancer Research

Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer

Lisha Xiang, Daniele M. Gilkes, Pallavi Chaturvedi, +5

Journal of Molecular Medicine

Breast OncologyMedicineBreast CancerHif-1 ActivityTriple-negative Breast Cancer +6

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype

Lisha Xiang, Daniele M. Gilkes, Hongxia Hu, +7

Oncotarget

Knock-down of glutaminase 2 expression decreases glutathione, NADH, and sensitizes cervical cancer to ionizing radiation

Lisha Xiang, Ganfeng Xie, Chen Liu, +7

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Cervical CancerRadiation EffectRadiation ExposureGynecologyGlutaminase 2 +5