Gut Dysbiosis during Influenza Contributes to Pulmonary Pneumococcal Superinfection through Altered Short-Chain Fatty Acid Production

Valentin Sencio, Adeline Barthélémy, Luciana P. Tavares, +21

Cell Reports

A druggable copper-signalling pathway that drives inflammation

Stéphanie Solier, Sebastian Müller, Tatiana Cañeque, +31

Nature

The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

Jan Wenzel, Josephine Lampe, Helge Müller‐Fielitz, +43

Nature Neuroscience

SARS-CoV-2 infection in nonhuman primates alters the composition and functional activity of the gut microbiota

Harry Sokol, Vanessa Contreras, Pauline Maisonnasse, +22

Gut Microbes

Alteration of the gut microbiota following SARS-CoV-2 infection correlates with disease severity in hamsters

Valentin Sencio, Arnaud Machelart, Cyril Robil, +21

Gut Microbes

Influenza Virus Infection Impairs the Gut’s Barrier Properties and Favors Secondary Enteric Bacterial Infection through Reduced Production of Short-Chain Fatty Acids

Valentin Sencio, Alexandre Gallerand, Marina Machado, +17

Infection and Immunity

Acetate Improves the Killing of Streptococcus pneumoniae by Alveolar Macrophages via NLRP3 Inflammasome and Glycolysis-HIF-1α Axis

Marina Machado, Thiago A. Patente, Yves Rouillé, +7

Frontiers in Immunology

Influenza infection rewires energy metabolism and induces browning features in adipose cells and tissues

Asma Ayari, Manuel Rosa‐Calatrava, Steve Lancel, +16

Communications Biology

Removal of senescent cells reduces the viral load and attenuates pulmonary and systemic inflammation in SARS-CoV-2-infected, aged hamsters

Lou Delval, Aline Hantute-Ghesquier, Valentin Sencio, +25

Nature Aging

Interleukin-22 Immunotherapy during Severe Influenza Enhances Lung Tissue Integrity and Reduces Secondary Bacterial Systemic Invasion

Adeline Barthélémy, Valentin Sencio, Daphnée Soulard, +4

Infection and Immunity

InflammationMucosal VaccinationInflammatory Lung DiseaseLung InflammationInterleukin-22 Immunotherapy +9