Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis

Elise Fouquerel, Ryan Barnes, Shikhar Uttam, +3

Molecular Cell

Genome InstabilityGeneticsMedicineCell BiologyOxidative Stress

ARTD1/PARP1 Negatively Regulates Glycolysis by Inhibiting Hexokinase 1 Independent of NAD+ Depletion

Elise Fouquerel, Eva M. Goellner, Zhongxun Yu, +11

Cell Reports

Oxidative guanine base damage regulates human telomerase activity

Elise Fouquerel, Justin D Lormand, Arindam Bose, +7

Nature Structural & Molecular Biology

Reductive StressGenome InstabilityMolecular BiologyHuman Telomerase ActivityCellular Senescence +4

Chemoptogenetic damage to mitochondria causes rapid telomere dysfunction

Wei Qian, Namrata Kumar, Vera Roginskaya, +8

Proceedings of the National Academy of Sciences

Mitochondrial FunctionBiochemistryCell DivisionPhotochemistryMitochondrial Dysfunction +10

PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms

Oliver Mortusewicz, Elise Fouquerel, Jean‐Christophe Amé, +2

Nucleic Acids Research

Dna DamageGeneticsMolecular BiologyMolecular ResearchTranscriptional Regulation +15

Radiation-induced mitotic catastrophe in PARG-deficient cells

Jean‐Christophe Amé, Elise Fouquerel, Laurent Gauthier, +5

Journal of Cell Science

Radiation EffectRadiation ExposureCell DeathMolecular BiologyCell Cycle +17

Damage sensor role of UV-DDB during base excision repair

Sunbok Jang, Namrata Kumar, Emily C. Beckwitt, +12

Nature Structural & Molecular Biology

Damage MechanismEngineeringWound HealingBiomedical EngineeringUv-c Irradiation +3

PARP1 associates with R-loops to promote their resolution and genome stability

Natalie Laspata, Parminder Kaur, Sofiane Y. Mersaoui, +10

Nucleic Acids Research

PARG is dispensable for recovery from transient replicative stress but required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress

Giuditta Illuzzi, Elise Fouquerel, Jean‐Christophe Amé, +5

Nucleic Acids Research

Genome InstabilityBiomanufacturingDetrimental AccumulationReplication ForksNatural Sciences +12

Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts

Dhvani Parikh, Elise Fouquerel, Connor T. Murphy, +2

Nature Communications