Wenxuan Zhen

Histone Deacetylase 3 Couples Mitochondria to Drive IL-1β-Dependent Inflammation by Configuring Fatty Acid Oxidation

Zhexu Chi, Sheng Chen, Ting Xu et al. · Molecular Cell · 2020 · 132 citations

Inflammation, Chromatin, Histone Deacetylase 3 +12

Tanshinone I, a new EZH2 inhibitor restricts normal and malignant hematopoiesis through upregulation of <i>MMP9</i> and <i>ABCG2</i>

Ying Huang, Shanhe Yu, Wenxuan Zhen et al. · Theranostics · 2021 · 65 citations · Full text

Gasdermin D maintains bone mass by rewiring the endo-lysosomal pathway of osteoclastic bone resorption

Mobai Li, Dehang Yang, Huige Yan et al. · Developmental Cell · 2022 · 54 citations

Physiology, Gasdermin D, Bone Remodeling +9

Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands

Nannan Su, Wenxuan Zhen, Heng Zhang et al. · Nature Chemical Biology · 2022 · 37 citations

Virus Structure, Signal Transduction, Biochemistry +5

Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel

Xiafei Yu, Yuan Xie, Xiaokang Zhang et al. · Cell Reports · 2021 · 33 citations · Full text