Steven Tessier

A novel mouse model of intervertebral disc degeneration shows altered cell fate and matrix homeostasis

Hyowon Choi, Steven Tessier, Elizabeth S. Silagi et al. · Matrix Biology · 2018 · 126 citations

Degenerative Spine, Developmental Biology, Molecular Neuroscience +8

Development of a standardized histopathology scoring system using machine learning algorithms for intervertebral disc degeneration in the mouse model—An <scp>ORS</scp> spine section initiative

Itzel Paola Melgoza, Srish S. Chenna, Steven Tessier et al. · JOR Spine · 2021 · 74 citations · Full text

TonEBP-deficiency accelerates intervertebral disc degeneration underscored by matrix remodeling, cytoskeletal rearrangements, and changes in proinflammatory gene expression

Steven Tessier, Victoria A. Tran, Olivia K. Ottone et al. · Matrix Biology · 2019 · 64 citations · Full text

Intervertebral Disc, Natural Sciences, Genetics +10

Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation

Steven Tessier, Alexandra C. Doolittle, Kimheak Sao et al. · JCI Insight · 2020 · 28 citations · Full text

Intervertebral Disc, Cell Death, Cytoskeleton +17

NFAT5/TonEBP controls early acquisition of notochord phenotypic markers, collagen composition, and sonic hedgehog signaling during mouse intervertebral disc embryogenesis

Steven Tessier, Vedavathi Madhu, Zariel I. Johnson et al. · Developmental Biology · 2019 · 24 citations · Full text

Cell Lineage, Developmental Biology, Bone Morphogenic Protein +10