Johannes N. Spelbrink

Premature ageing in mice expressing defective mitochondrial DNA polymerase

Aleksandra Trifunović, Anna Wredenberg, Maria Falkenberg et al. · Nature · 2004 · 2.7K citations

Aging, Mitochondrial Function, Longevity +3

Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria

Johannes N. Spelbrink, Fang-Yuan Li, Valeria Tiranti et al. · Nature Genetics · 2001 · 879 citations

Mitochondrial Biogenesis, Mitochondrial Function, Mitochondrial Dynamic +8

Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production

Aleksandra Trifunović, Anna Hansson, Anna Wredenberg et al. · Proceedings of the National Academy of Sciences · 2005 · 555 citations · Full text

Mitochondrial Theory, Dna Damage, Aging +18

TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions

Inmaculada Martínez‐Reyes, Lauren Diebold, Hyewon Kong et al. · Molecular Cell · 2015 · 512 citations

Mitophagy, Signal Transduction, Mitochondrial Function +7

Composition and Dynamics of Human Mitochondrial Nucleoids

Nuria Garrido, Lorena Griparić, Eija Jokitalo et al. · Molecular Biology of the Cell · 2003 · 363 citations · Full text