DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection

Mark J. Walker, Andrew Hollands, Martina Sanderson‐Smith, +12

Nature Medicine

Natural SciencesVirulence FactorPathogenesisMolecular BiologyDna Replication +9

A Systematic and Functional Classification of Streptococcus pyogenes That Serves as a New Tool for Molecular Typing and Vaccine Development

Martina Sanderson‐Smith, David M. P. De Oliveira, Julien Guglielmini, +15

The Journal of Infectious Diseases

VaccinationReverse VaccinologyVaccine DevelopmentVirulence FactorVaccine Target +13

The Classical Lancefield Antigen of Group A Streptococcus Is a Virulence Determinant with Implications for Vaccine Design

Nina M. van Sorge, Jason N. Cole, Kirsten Kuipers, +22

Cell Host & Microbe

VaccinationReverse VaccinologyVaccine DevelopmentVaccine TargetPathogenesis +9

Host and pathogen hyaluronan signal through human siglec-9 to suppress neutrophil activation

Ismael Secundino, Anel Lizcano, K. Markus Roupé, +9

Journal of Molecular Medicine

InflammationNeutrophil ActivationAllergyGranulocyteImmunology +6

Structure-Informed Design of an Enzymatically Inactive Vaccine Component for Group A <i>Streptococcus</i>

Anna Henningham, Daniel J. Ericsson, Karla Langer, +7

mBio

Differing Efficacies of Lead Group A Streptococcal Vaccine Candidates and Full-Length M Protein in Cutaneous and Invasive Disease Models

Tania Rivera-Hernández, Manisha Pandey, Anna Henningham, +13

mBio

Conserved anchorless surface proteins as group A streptococcal vaccine candidates

Anna Henningham, Emiliano Chiarot, Christine M. Gillen, +16

Journal of Molecular Medicine

VaccinationVaccine DevelopmentMedicineVaccine TargetPathogenesis +7

Virulence Role of the GlcNAc Side Chain of the Lancefield Cell Wall Carbohydrate Antigen in Non-M1-Serotype Group A<i>Streptococcus</i>

Anna Henningham, Mark R. Davies, Satoshi Uchiyama, +6

mBio

Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone

Peter G. Maamary, Nouri L. Ben Zakour, Jason N. Cole, +17

The FASEB Journal

World Health OrganizationMicrobial PathogensGeneticsGenomicsBacterial Pathogens +17

Human pathogenic streptococcal proteomics and vaccine development

Jason N. Cole, Anna Henningham, Christine M. Gillen, +2

PROTEOMICS - CLINICAL APPLICATIONS