Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur

Zhenming Jin, Yao Zhao, Yuan Sun, +18

Nature Structural & Molecular Biology

Antineoplastic Drug CarmofurAntiviral CompoundBiochemistryMedicineAntiviral Drug Development +7

Calcium channel blocker amlodipine besylate therapy is associated with reduced case fatality rate of COVID-19 patients with hypertension

Leike Zhang, Yuan Sun, Hao‐Long Zeng, +13

Cell Discovery

Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2

Rui Xiong, Leike Zhang, Shiliang Li, +22

Protein & Cell

White-Opaque Switching in Natural MTLa/α Isolates of Candida albicans: Evolutionary Implications for Roles in Host Adaptation, Pathogenesis, and Sex

Jing Xie, Tao Li, Clarissa J. Nobile, +9

PLoS Biology

BiologyFungal Cell BiologyGeneticsPathogenesisMtl Homozygotes +11

Roles of Candida albicans Gat2, a GATA-Type Zinc Finger Transcription Factor, in Biofilm Formation, Filamentous Growth and Virulence

Han Du, Guobo Guan, Jing Xie, +4

PLoS ONE

Fungal Developmental BiologyBiofilm DevelopmentBiofilm FormationFungal Cell BiologyCandida Albicans +11

Oxidative stress induces downregulation of TP53INP2 and suppresses osteogenic differentiation of BMSCs during osteoporosis through the autophagy degradation pathway

Yuehua Yang, Yuan Sun, Weiwei Mao, +3

Free Radical Biology and Medicine

Cell AutophagyMitophagyBone Morphogenic ProteinMedicinePhysiology +9

Unique Photochemo-Immuno-Nanoplatform against Orthotopic Xenograft Oral Cancer and Metastatic Syngeneic Breast Cancer

Lu Zhang, Di Jing, Lei Wang, +6

Nano Letters

Unique Photochemo-immuno-nanoplatformNanomedicineNanotherapeuticsEngineeringTherapeutic Nanomaterials +13

Neuroprotective Effect of Salvianolic Acids against Cerebral Ischemia/Reperfusion Injury

Shuai Hou, Mingming Zhao, Pingping Shen, +3

International Journal of Molecular Sciences

Lipid PeroxidationCell DeathRedox BiologyCerebral Vascular RegulationOxidative Stress +15

Immunoglobulin fragment F(ab’)2 against RBD potently neutralizes SARS-CoV-2 in vitro

Xiaoyan Pan, Pengfei Zhou, Tiejiong Fan, +12

Antiviral Research

The transcription factor Flo8 mediates CO₂sensing in the human fungal pathogen<i>Candida albicans</i>

Han Du, Guobo Guan, Jing Xie, +5

Molecular Biology of the Cell