Lan-Ying Qin

Synthesis and SAR studies of trisubstituted purinones as potent and selective adenosine A2A receptor antagonists

Yuefei Shao, Andrew G. Cole, Marc‐Raleigh Brescia et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 29 citations · Full text

Molecular Pharmacology, Biochemistry, Medicine +5

Identification of a Potent, Selective, and Efficacious Phosphatidylinositol 3-Kinase δ (PI3Kδ) Inhibitor for the Treatment of Immunological Disorders

Qingjie Liu, Qing Shi, David Marcoux et al. · Journal of Medicinal Chemistry · 2017 · 22 citations · Full text

Immunodeficiencies, Immunological Disorders, Immunology +24

Discovery of 7-(3-(piperazin-1-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives as highly potent and selective PI3Kδ inhibitors

Lan-Ying Qin, Zheming Ruan, Robert J. Cherney et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 16 citations · Full text

Medicinal Chemistry, Biochemistry, Selective Pi3kδ Inhibitors +8

A multicentre randomized double-blind placebo-controlled phase III study of the efficacy and safety of xeligekimab (GR1501) in patients with moderate-to-severe plaque psoriasis

Lin Cai, Congjun Jiang, Guoqiang Zhang et al. · British Journal of Dermatology · 2024 · 15 citations

Solid-phase synthesis of N-9-substituted 2,8-diaminopurines

Andrew G. Cole, Axel Metzger, Gulzar Ahmed et al. · Tetrahedron Letters · 2006 · 14 citations

Synthesis Method, Synthetic Chemistry, Solid-phase Synthesis +1