Xinshan Kang

Hierarchical Database Screenings for HIV-1 Reverse Transcriptase Using a Pharmacophore Model, Rigid Docking, Solvation Docking, and MM−PB/SA

Junmei Wang, Xinshan Kang, Irwin D. Kuntz et al. · Journal of Medicinal Chemistry · 2005 · 63 citations

Synthesis and biological evaluation of crown ether fused quinazoline analogues as potent EGFR inhibitors

Shaojing Hu, Guojian Xie, Don X. Zhang et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 61 citations · Full text

Medicinal Chemistry, Potent Egfr Inhibitors, Quinazoline Analogues +8

Discovery of 3,3‘-(2,4-Diaminopteridine-6,7-diyl)diphenol as an Isozyme-Selective Inhibitor of PI3K for the Treatment of Ischemia Reperfusion Injury Associated with Myocardial Infarction

Moorthy S. S. Palanki, Elena Dneprovskaia, John Doukas et al. · Journal of Medicinal Chemistry · 2007 · 55 citations · Full text

Pi3k Inhibitors, Cardiovascular Pharmacology, Pharmacotherapy +16

Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine—a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays

Glenn Noronha, Kathy Barrett, Antonio Boccia et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 46 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Chemistry +13

Development of Prodrug 4-Chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-1,2,4-benzotriazin-7-yl)phenyl Benzoate (TG100801): A Topically Administered Therapeutic Candidate in Clinical Trials for the Treatment of Age-Related Macular Degeneration

Moorthy S. S. Palanki, Hideo Akiyama, Peter A. Campochiaro et al. · Journal of Medicinal Chemistry · 2008 · 44 citations · Full text