Concepedia

Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine—a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays

Glenn Noronha, Kathy Barrett, Antonio Boccia, Tessa Brodhag, Jianguo Cao, Chun P. Chow, Elena Dneprovskaia, John Doukas, Richard Fine, Xianchang Gong,

Bioorganic & Medicinal Chemistry Letters · 2006 · 47 citations · 22 references

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References

22

Tumor Regression by Targeted Gene Delivery to the Neovasculature

John Hood, Mark D. Bednarski, Ricardo F. Frausto et al. · Science · 2002 · 858 citations

, , +17

Selective Requirement for Src Kinases during VEGF-Induced Angiogenesis and Vascular Permeability

Brian P. Eliceiri, Robert Paul, Pamela L. Schwartzberg et al. · Molecular Cell · 1999 · 817 citations · Full text

, , +17

Increase in activity and level of pp60c-src in progressive stages of human colorectal cancer.

Mark S. Talamonti, Mark S. Roh, S. Curley et al. · Journal of Clinical Investigation · 1993 · 397 citations · Full text

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A Versatile Method for Suzuki Cross‐Coupling Reactions of Nitrogen Heterocycles

Noriaki Kudo, M. Perseghini, Gregory C. Fu · Angewandte Chemie International Edition · 2006 · 365 citations

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Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke

Robert Paul, Zheng G. Zhang, Brian P. Eliceiri et al. · Nature Medicine · 2001 · 343 citations

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