James Randazzo

Cellular osmolytes reduce lens epithelial cell death and alleviate cataract formation in galactosemic rats.

Michael L. Mulhern, Christian J. Madson, Peter F. Kador et al. · PubMed · 2007 · 56 citations

Life Sciences, Biochemistry, Ophthalmology +14

Osmotic stress, not aldose reductase activity, directly induces growth factors and MAPK signaling changes during sugar cataract formation

Peng Zhang, Kuiyi Xing, James Randazzo et al. · Experimental Eye Research · 2012 · 42 citations · Full text

Life Sciences, Biochemistry, Cell Biology +8

Orally Active Multi-Functional Antioxidants Delay Cataract Formation in Streptozotocin (Type 1) Diabetic and Gamma-Irradiated Rats

James Randazzo, Peng Zhang, Jun Makita et al. · PLoS ONE · 2011 · 39 citations · Full text

Life Sciences, Ophthalmology, Pharmacology +16

Multifunctional Antioxidants for the Treatment of Age-Related Diseases

Hong‐Xia Jin, James Randazzo, Peng Zhang et al. · Journal of Medicinal Chemistry · 2010 · 39 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Effects of topical administration of an aldose reductase inhibitor on cataract formation in dogs fed a diet high in galactose

Peter F. Kador, Daniel M. Betts, Milton Wyman et al. · American Journal of Veterinary Research · 2006 · 33 citations · Full text

Medicine, Ophthalmology, Veterinary Ophthalmology +15