Leen Mathys

Tryptophan dendrimers that inhibit HIV replication, prevent virus entry and bind to the HIV envelope glycoproteins gp120 and gp41

Eva Rivero‐Buceta, Elisa G. Doyagüez, Ignacio Colomer et al. · European Journal of Medicinal Chemistry · 2015 · 35 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +11

Potent antiviral activity of carbohydrate-specific algal and leguminous lectins from the Brazilian biodiversity

Ana C. S. Gondim, Suzete Roberta da Silva, Leen Mathys et al. · MedChemComm · 2019 · 35 citations · Full text

Life Sciences, Biochemistry, Biology +13

Deletion of the Highly Conserved N-Glycan at Asn260 of HIV-1 gp120 Affects Folding and Lysosomal Degradation of gp120, and Results in Loss of Viral Infectivity

Leen Mathys, Katrien O. François, Matthias Quandte et al. · PLoS ONE · 2014 · 32 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Several N-Glycans on the HIV Envelope Glycoprotein gp120 Preferentially Locate Near Disulphide Bridges and Are Required for Efficient Infectivity and Virus Transmission

Leen Mathys, Jan Balzarini · PLoS ONE · 2015 · 20 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition

Kathrin Reiser, Leen Mathys, Sophie Curbo et al. · PLoS ONE · 2016 · 16 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16