Steven A. Lubitz

The mutational constraint spectrum quantified from variation in 141,456 humans

Konrad J. Karczewski, Laurent C. Francioli, Grace Tiao et al. · Nature · 2020 · 10.1K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

Amit V. Khera, Mark Chaffin, Krishna G. Aragam et al. · Nature Genetics · 2018 · 3.1K citations

Life Sciences, Genetics, Molecular Genetics +16

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

Daniel Taliun, Daniel Harris, Michael D. Kessler et al. · Nature · 2021 · 2.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study

Renate B. Schnabel, Xiaoyan Yin, Philimon Gona et al. · The Lancet · 2015 · 1.7K citations

Medicine, Cardiology, Clinical Cardiology +11

A genomic mutational constraint map using variation in 76,156 human genomes

Siwei Chen, Laurent C. Francioli, Julia K. Goodrich et al. · Nature · 2023 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +14