The activated conformation of integrin β7 is a novel multiple myeloma–specific target for CAR T cell therapy

Naoki Hosen, Yukiko Matsunaga, Kana Hasegawa, +30

Nature Medicine

Cancer ImmunosurveillanceImmunologyCellular Immune ResponseIntegrin β7Immunotherapy +3

Markedly improved outcomes and acceptable toxicity in adolescents and young adults with acute lymphoblastic leukemia following treatment with a pediatric protocol: a phase II study by the Japan Adult Leukemia Study Group

Fumihiko Hayakawa, Toru Sakura, Toshiaki Yujiri, +20

Blood Cancer Journal

Hematological MalignancyYoung AdultsOncologyAdolescent MedicinePediatric Epidemiology +11

CD138-negative clonogenic cells are plasma cells but not B cells in some multiple myeloma patients

Naoki Hosen, Yoshikazu Matsuoka, Satoshi Kishida, +19

Leukemia

Hematological MalignancyImmunologyHematologyCd138-negative Clonogenic CellsMultiple Myeloma Patients +4

CD48 as a novel molecular target for antibody therapy in multiple myeloma

Naoki Hosen, Hiroyoshi Ichihara, Atsuko Mugitani, +16

British Journal of Haematology

Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chain

Kana Hasegawa, Shunya Ikeda, Moto Yaga, +46

Science Translational Medicine

Infliximab for the Treatment of Severe Steroid Refractory Acute Graft-versus-host Disease in Three Patients after Allogeneic Hematopoietic Transplantation

Takahisa Yamane, Ryousuke Yamamura, Yasutaka Aoyama, +7

Leukemia & lymphoma/Leukemia and lymphoma

Cell TherapyImmunologyTransplantation MedicineSevere AgvhdImmunotherapy +16

Phase II study of imatinib‐based chemotherapy for newly diagnosed <i>BCR‐ABL‐</i>positive acute lymphoblastic leukemia

Shin Fujisawa, Shuichi Mizuta, Hideki Akiyama, +14

American Journal of Hematology

Acute rhabdomyolysis following administration of high-dose cyclophosphamide: case report

Etsuko Shima, Masayuki Hino, Takahisa Yamane, +9

Annals of Hematology

Clinical Case ReportHematologyTherapeutic ControversyCase SeriesPharmacotherapy +2

The Prophylactic Effect of Itraconazole Capsules and Fluconazole Capsules for Systemic Fungal Infections in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndromes: A Japanese Multicenter Randomized, Controlled Study

Yoshikazu Ito, Kazuma Ohyashiki, Isao Yoshida, +12

International Journal of Hematology

Antifungal AgentFluconazole CapsulesAcute Myeloid LeukemiaPharmacologyClinical Mycology +4

Blastic NK-cell lymphoma/leukemia with T-cell receptor γ rearrangement

Yasutaka Aoyama, Takahisa Yamane, Masayuki Hino, +8

Annals of Hematology

Lymphoid NeoplasiaBlastic Nk-cell Lymphoma/leukemiaImmunologyTumor ImmunityT Cell Immunity +2