Chemerin Exacerbates Glucose Intolerance in Mouse Models of Obesity and Diabetes

Matthew C. Ernst, Mark E. Issa, Kerry B. Goralski, +1

Endocrinology

AdipokinesInsulin SignalingGastrointestinal Peptide HormoneObesityMetabolic Syndrome +15

Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses

Fan Huang, Christophe Gonçalves, Margarita Bartish, +30

Journal of Clinical Investigation

ImmunologyMnk1/2-eif4e Axis ImpairsImmune Cell TherapyImmunotherapyTumor Biology +17

Chemokine-like receptor 1 regulates skeletal muscle cell myogenesis

Mark E. Issa, Shanmugam Muruganandan, Matthew C. Ernst, +5

American Journal of Physiology-Cell Physiology

Cytotoxic flavonoids and other constituents from the stem bark of<i>Ochna schweinfurthiana</i>

Joseph Thierry Ndongo, Mark E. Issa, Angélique Nicolas Messi, +4

Natural Product Research

Jadomycins are cytotoxic to ABCB1-, ABCC1-, and ABCG2-overexpressing MCF7 breast cancer cells

Mark E. Issa, Steven R. Hall, Stephanie N. Dupuis, +3

Anti-Cancer Drugs

Jadomycins BBreast OncologyMultidrug ResistanceCancer BiologyTumor Biology +14

Bruceantin inhibits multiple myeloma cancer stem cell proliferation

Mark E. Issa, Sarah Berndt, Gilles Carpentier, +2

Cancer Biology & Therapy

Hematological MalignancyTumor BiologyOncologyMedicineTumor Growth +10

Hydroxyl Ketone-Based Histone Deacetylase Inhibitors To Gain Insight into Class I HDAC Selectivity versus That of HDAC6

Mohamed Dit Mady Traoré, Vincent Zwick, Cláudia A. Simões‐Pires, +8

ACS Omega

Withaferin A induces cell death and differentiation in multiple myeloma cancer stem cells

Mark E. Issa, Muriel Cuendet

MedChemComm

Withanolide D Exhibits Similar Cytostatic Effect in Drug-Resistant and Drug-Sensitive Multiple Myeloma Cells

Mark E. Issa, E. M. Kithsiri Wijeratne, A. A. Leslie Gunatilaka, +1

Frontiers in Pharmacology

Hydroxychloroquine (HCQ) decreases the benefit of anti-PD-1 immune checkpoint blockade in tumor immunotherapy

Janna Krueger, François Santinon, Alexandra Kazanova, +5

PLoS ONE

Tumor BiologyTumor ImmunologyCancer ImmunosurveillancePd-l1 ExpressionMedicine +13