Concepedia

Author

Joost Schimmel

Leiden University Medical CenterORCID

Also Known As

Joost Schimmel

32

Publications

2.2K

Citations

16

H-Index

48

Concepts

All Affiliations

Leiden University Medical CenterLeiden UniversityNovo Nordisk FoundationErasmus MCMax Planck Institute of Biochemistry
JS

About

Joost Schimmel is an author at Leiden University Medical Center specializing in medicine, cell biology, and molecular biology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

9

9

711

2

Natural Sciences

5

5

559

3

Engineering

2

2

44

4

Biochemistry

1

1

11

5

Biology

1

1

28

Joost Schimmel

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20

Publications

2.1K

Citations

16

H-Index

YearCitations

Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance

Diana Zatreanu, Helen M.R. Robinson, Omar Alkhatib,

Nature Communications

2021

336

Site-Specific Identification of SUMO-2 Targets in Cells Reveals an Inverted SUMOylation Motif and a Hydrophobic Cluster SUMOylation Motif

Ivan Matić, Joost Schimmel, Ivo A. Hendriks,

Molecular Cell

2010

305

In Vivo Identification of Human Small Ubiquitin-like Modifier Polymerization Sites by High Accuracy Mass Spectrometry and an in Vitro to in Vivo Strategy

Ivan Matić, Martijn van Hagen, Joost Schimmel,

Molecular & Cellular Proteomics

2007

297

Uncovering SUMOylation Dynamics during Cell-Cycle Progression Reveals FoxM1 as a Key Mitotic SUMO Target Protein

Joost Schimmel, Karolin Eifler, Jón Otti Sigurðsson,

Molecular Cell

2014

174

The Ubiquitin-Proteasome System Is a Key Component of the SUMO-2/3 Cycle

Joost Schimmel, Katja M. Larsen, Ivan Matić,

Molecular & Cellular Proteomics

2008

151

Mutational signatures of non‐homologous and polymerase theta‐mediated end‐joining in embryonic stem cells

Joost Schimmel, Hanneke Kool, Robin van Schendel,

The EMBO Journal

2017

147

MEF2 Activates a Genetic Program Promoting Chamber Dilation and Contractile Dysfunction in Calcineurin-Induced Heart Failure

Ralph J. van Oort, Eva van Rooij, Meriem Bourajjaj,

Circulation

2006

135

Inactivation of Pol θ and C-NHEJ eliminates off-target integration of exogenous DNA

Alex N. Zelensky, Joost Schimmel, Hanneke Kool,

Nature Communications

2017

127

RNF12 Controls Embryonic Stem Cell Fate and Morphogenesis in Zebrafish Embryos by Targeting Smad7 for Degradation

Long Zhang, Huizhe Huang, Fangfang Zhou,

Molecular Cell

2012

95

Modulating mutational outcomes and improving precise gene editing at CRISPR-Cas9-induced breaks by chemical inhibition of end-joining pathways

Joost Schimmel, Núria Muñoz-Subirana, Hanneke Kool,

Cell Reports

2023

66

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